EULAR guidelines on ANCA-associated vasculitis in the real life
نویسندگان
چکیده
Anti-neutrophil cytoplasmic antibodies-associated vasculitides (AAVs) are a heterogenous group of inflammatory diseases which primarily involve small vessels and include granulomatosis with polyangiitis (GPA), microscopic (MPA) eosinophilic (EGPA). They present heterogeneous clinical manifestations, while their diagnosis management still remain challenge for clinicians. Nowadays, the treatment is based on two different regimens: remission-induction remission-maintenance treatment. The therapeutic armamentarium has grown over years, aim to lessen adverse effects, improve quality life patients maintain disease under control. Biological treatments future: they act pathogenic pathways may offer in future personalized approach tailored actual manifestations. latest guidelines were published 2015 by European League Against Rheumatism (EULAR) represent vade mecum AAVs. In this review, we will focus principal strategies treat We discuss therapy remission- maintenance therapy; have also distinguished GPA MPA from that EGPA, because pictures.
منابع مشابه
The CARI guidelines. ANCA serology in the diagnosis and management of ANCA-associated renal vasculitis.
a. Serum anti-neutrophil cytoplasmic antibody (ANCA) measurement should not be used alone in the initial diagnosis of ANCA-associated vasculitis (AAV) but should be used in combination with the gold standard of tissue diagnosis. (Level 1 evidence) b. Measurement of ANCA by both ELISA and indirect immunofluorescence (IIF) in combination ensures optimal test sensitivity and specificity. (Level I ...
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ژورنال
عنوان ژورنال: Beyond rheumatology
سال: 2021
ISSN: ['2612-5110']
DOI: https://doi.org/10.4081/br.2020.50